Chromatin remodelers, in cooperation with lncRNAs, are closely involved in tumor-associated inflammation, such as in the disruption of lncRNA MALAT1, which impairs the recruitment of the chromatin remodeler catalytic subunit SMARCA4 to the promoter regions of IL-6 and CXCL8, resulting in NF-κB pathway activation and HCC progression [164]. Here, SMARCA4 is linked to neoplasm.