Recent studies found that a circRNA derived from of the SMARCA5 gene (circ-SMARCA5) is involved in the occurrence of several cancers [90], such as circ-SMARCA5 in bladder cancer, which was found to be a potential prognostic marker correlated with advanced tumor features and poor survival [62], and circ-SMARCA5 in breast cancer, which was observed to be silent and correlated with the drug sensitivity of breast cancer cell lines [63]. The gene discussed is SMARCA5; the disease is cancer.