Additional pathways discovered were: hereditary breast cancer, the role of tissue factor in cancer, neuregulin, retinoic acid-mediated apoptosis, mismatch repair in eukaryotes, ERBB, PI3K/AKT, DNA damage-induced 14-3-3σ, GADD45, germ cell-sertoli cell junction, MYC mediated apoptosis, NGF, and HER-2 signaling pathways. This evidence concerns the gene AKT1 and breast cancer.