RYR1 and myopathy: Previous complications or deaths in anesthesia in personal or family history, suspicion to or known myopathy, recurrent or idiopathic rhabdomyolysis, idiopathic hyperCKemia, exertional heat stroke, detected non-benign variants in genes causally connected with MH or Excitation-Contraction Coupling (nowadays known RYR1, CACNA1S or STAC3, but might be also other genes in the future).