They reported that VDR protein expression on CD4+ T helper (Th) cells and their subsets, especially Th1, T regulatory (Treg), and T follicular helper cells (Tfh), was increased in SLE; additionally, VDR expression was positively associated with clinical disease activity and cell apoptosis in SLE patients [60]. The gene discussed is CD4; the disease is systemic lupus erythematosus.