Similarly, our results demonstrate altered expression profiles of the genes associated with B cell differentiation and the B cell receptor-signaling pathways (CD79B, BLNK, CD72, LYN, BTLA and IRF1) in the relapsed AML cells, indicating that B cells-mediated immune processes might have an effect on post-transplant relapse. The gene discussed is CD79B; the disease is acute myeloid leukemia.