The dynamic of the changes in examined parameters was shown as a gradual decrease in the PON1 concentration in smoking AP patients with the GG (p = 0.0234 for comparison the first day with the seventh day) and AG genotypes (p < 0.0001 for comparison on the first day with the third day and p = 0.0003 for comparison the first day with the seventh day). This evidence concerns the gene PON1 and alkaline phosphatase measurement.