In the blood of AP patients with the AG genotype was also observed the highest PON1(L) activity, which was statistically significant to the AP patients with the GG (p = 0.0099 and p = 0.019 on the first and third days of hospitalization, respectively) and AA genotype (p = 0.0107 on the third day). The gene discussed is PON1; the disease is alkaline phosphatase measurement.