It was found that a gradually decreasing PON1(L) activity during the hospitalization of AP patients with the CC genotype (p = 0.0105 and p = 0.0435 for comparison of the first with seventh day and the third with the seventh day, respectively), in contrast to the group of AP patients with the TC genotype (p = 0.0066 for comparison of AP patients with the CC and TC genotypes on the seventh day). Here, PON1 is linked to alkaline phosphatase measurement.