The activity of PON1(P) in the blood of AP patients was noted to be lower than in healthy subjects (p < 0.0001 and p = 0.0003 for women and men, respectively), which was accompanied by lower HDL concentrations (p = 0.0018 and p = 0.0307 for women and men, respectively) (Table 2). The gene discussed is PON1; the disease is alkaline phosphatase measurement.