The results did not reveal an overall association between the investigated SNPs (ACE2 rs2285666, ACE2 rs2074192, TMPRSS2 rs12329760, TMPRSS2 rs2070788) and long-COVID symptomatology suggesting that SNPs of ACE2 and TMPRSS2 genes do not predispose for developing long-COVID symptoms in previously hospitalized COVID-19 survivors. The gene discussed is ACE2; the disease is COVID-19.