By analyzing the changes of indicators, weight, fasting blood sugar, and other bio-physiological parameters such as total cholesterol (TC), triglyceride (TG), superoxide dismutase (SOD), and catalase (CAT), combined with high-throughput sequencing, the effect of MBP on the intestinal flora in T2DM was elucidated. This evidence concerns the gene CAT and type 2 diabetes mellitus.