The findings showed that SA showed a stronger action at a dose of 40 mg/kg body weight, which was measured by the increase in antioxidant defense (superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx)), a reduction in tumor incidence, and the modulation of LPO markers, including phase I (CYP450 and CYP2E1) and phase II Glutathione-S-transferase (GST), DT-Diaphorase (DTD), and UDP-Glucuronyl transferase (UDP-GT) detoxification enzymes [71]. The gene discussed is NQO1; the disease is neoplasm.