In prostate cancer, stem-like cells were seen to overexpress various genes linked to JAK/STAT signaling pathway, such as IFNK, IFNGR, IL6, CSF2, and STAT1 [157], and stimulate STAT3 to prominently regulate JAK/STAT signaling molecules in mammalian CSC-like cells [158]. This evidence concerns the gene STAT3 and prostate cancer.