This poses a major obstacle in anti-tumor therapies, hence it is necessary to develop therapeutics targeting such lncRNAs such as lncARSR, lncRNA-cCSC1, and lncRNA THOR, for incurring chemo-drug resistance, and lncRNA TUG1 for causing radio-resistance, and many more that are responsible in different cancer types. Here, TUG1 is linked to cancer.