STING-associated vasculopathy with onset in infancy (SAVI), classified as an interferonopathy i.e., a disorder associated with an upregulation of interferon, is an autoinflammatory disease with early onset systemic inflammation, skin lesions, failure to thrive and perivascular inflammation associated with high interferon-stimulated gene (ISG) expression profile [96,97]. The gene discussed is STING1; the disease is Failure to thrive.