In addition, MUC1 and IGF1R co-expressed with CTD-2566J3.1 had AUC > 0.6 and were found significantly over-expressed in patients without response to therapy, indicating that down-regulation of these mRNAs can modestly discriminate PCR in patients with luminal B breast cancer (Figure 9D–G). The gene discussed is IGF1R; the disease is breast cancer.