STAR and hydrops fetalis: The expression of key steroidogenic proteins in the ovary of HFD-HF diet-fed rats showed decreased StAR, CYP11A1, 3βHSD, and 17βHSD (Figure 5C–E,G) as well as testosterone metabolizing enzyme P450 aromatase (Figure 5G), although CYP17A1 expression unaltered (Figure 5F).