These included DNA replication, progesterone-mediated oocyte maturation, cell cycle, alcoholism, homologous recombination, base excision repair, nucleotide excision repair, viral carcinogenesis, oocyte meiosis, the p53 signaling pathway, mismatch repair, the Fanconi anemia pathway, the spliceosome, microRNAs in cancer, pyrimidine metabolism, and RNA degradation (Figure 10F). The gene discussed is TP53; the disease is alcohol dependence.