In accordance, a link between ILK and Hippo pathway has been previously evidenced in cancer, as the inhibition of ILK in different types of cancer resulted in the activation of the the Hippo pathway components MST1 and LATS1 with concomitant inactivation of YAP/TAZ transcriptional co-activators and TEAD-mediated transcription [21]. The gene discussed is ILK; the disease is cancer.