The expression of ILK in normal skin was negative, while positive cytoplasmic expression of ILK was observed in the epidermis basal layer in 100% of HS and KS (38/38 and 55/55 cases, respectively), in appendages and blood vessels in 34/38 HS and 52/55 KS, respectively, and fibroblasts in 37/38 and 54/55 cases of HS and KS, respectively (Figure 2). This evidence concerns the gene ILK and histiocytic sarcoma.