TREM2 and Alzheimer disease: Although no significant changes were detected for TGF-β, IL-10, IL-6, MHC-II, CX3CR1 and CD68 (Figure 4E), an increased immunofluorescence signal was found for iNOS (p < 0.001), with a decrease in Arg-1 (p < 0.01) and TREM2 (p < 0.05) in MG-AD vs. MG-Ctrl (Figure 4F,G).