ACE and cardiac hypertrophy: Apart from AT1R blockers, ACE inhibitors such as enalapril, ramipril, benazepril, zofenopril, lisinopril, fosinopril, perindopril, and imidapril which reduce the formation of Ang II, have been evidenced for their beneficial effects in attenuating pathological cardiac hypertrophy [27,161,162,163,164,165,166,167].