In a prospective study that included 94 women with a history of RIF or recurrent pregnancy loss, Bouet et al. [49] reported that the sensitivity, specificity, and positive and negative predictive values of the presence of endometrial micropolyps and hyperemia were 40%, 80%, 35%, and 83%, respectively, resulting in an accuracy of 71%, when histopathologic CE was defined as ≥5 CD138(+) ESPC in 10 HPFs. This evidence concerns the gene SDC1 and cholesteryl ester measurement.