HTRA1 and gestational diabetes: Interestingly, we found that the median of HtrA1 concentration of GDM pregnancies was 4.3 ng/mL (IQR: 3.4;6.0) while in normal pregnancies was 1.9 ng/mL (IQR: 0.8;4.0), showing that pregnancy complicated by GDM had a statistically significant higher concentrations of HtrA1 compared to healthy pregnancies (p = 0.004), proving that HtrA1 is altered in pregnancy complicated by GDM.