Acromegaly, a disease induced by a pituitary GH (Growth Hormone) producing tumors in 95% of cases, is part of a larger category of endocrine entities associated with hypophyseal tumors with an increasing ratio in the general population (incidence and prevalence of 3.9–7.4, respective 76–116 cases per 100,000 per year, respectively, particularly for acromegaly, with values of 0.2–1.1 and 2.8–13.7, respectively) [1,2]. The gene discussed is GH1; the disease is acromegaly.