Animals were euthanized at 5 weeks due to tumor size at which time tumor volumes were higher in SH-SY5Y sgRNA-PHF14 inoculated mice compared to controls [tumor weight (g); control, 0.467 ± 0.39 versus sgRNA-PHF14, 1.5 ± 0.21, p < 0.0005, Figure 5B], confirming the tumor inhibitory effect of PHF14 in vivo. Here, PHF14 is linked to neoplasm.