IFI16 and ovarian carcinoma: It has been demonstrated that ovarian cancer with somatic DDR mutation presents a separate immune profile with high expression of LAG-3, CCL5 (C-C motif chemokine ligand 5), IFI16 (interferon gamma inducible protein 16), PTPRCAP (protein tyrosine phosphatase receptor type C-associated protein), IL15RA (interleukin 15 Receptor Subunit Alpha) and GBP1 (Guanylate Binding Protein 1) [91].