Taking into account the studies that suggest a reduced concentration of soluble form of SDC1 in blood can be a risk factor for PE [33], and that its increased concentration can predict the occurrence of multiple organ failure in various pathological conditions [13], the identified correlation between SDC1 concentration and hemodynamic parameters both in healthy and pathological pregnancy shows its dual role and the existence of a concentration–effect relationship. The gene discussed is SDC1; the disease is Multiple Organ Failure.