The prevalence rates of hypertension (p = 0.007) and the use of anti-hypertensives (p = 0.003) in the group with low cystatin C were significantly lower than those in the group with high cystatin C. The group with low cystatin C had significantly lower levels of blood urea nitrogen (p = 0.007), creatinine (p < 0.001), and uric acid (p = 0.018) but higher eGFR (p < 0.001) and albumin (p < 0.001) levels than the group with high cystatin C. With regard to the biomarkers, the low cystatin C group had a significantly lower total vitamin D (p = 0.028) and adiponectin (p = 0.002) levels. The gene discussed is CST3; the disease is Hypertension.