VEGFA and choroidal neovascularization: nvAMD is mainly driven by an imbalance of angiogenic and anti-angiogenic factors favoring an overexpression of the angiogenic vascular endothelial growth factor (VEGF) and including Choroidal Neovascularization (CNV), which requires frequent, often monthly life-long intraocular injection of inhibitors of VEGF [15,16].