APEX1 and breast cancer: Logistic regression and ROC analyses showed that a panel including EV miRNAs (miR-139, miR-136, miR-19, and miR-210) and EV proteins (BLCA-4, NMP22, APE1/Ref1, CRK, and VIM) were able to discriminate BC patients from healthy subjects with an AUC = 0.903.