There was a difference in the rate of hypermethylation that was identified in the promoters SHP1, SOCS1, and SOCS3 [183]; the increased expression of JAK/STAT signalling in MM may be attributed to the fact that SOCS1 and SOCS3 are targets for the miR-17–92 cluster. The gene discussed is SOAT1; the disease is Miyoshi myopathy.