Previous studies reported that the TERT variant rs2736100 is associated with TL and multiple disease risks, including colorectal cancer, myeloproliferative neoplasms [21], primary glomerulonephritis/end-stage renal disease [25], decreased idiopathic pulmonary fibrosis, combined pulmonary fibrosis, and emphysema syndrome [26]. The gene discussed is TERT; the disease is colorectal cancer.