Based on these findings, they concluded that the pro-atherosclerotic microenvironment, including hypercholesterolemia and inflammatory cytokines like M-CSF, allows the induction of TCTP expression in macrophages and this protects macrophages against Bax-induced apoptosis, thereby facilitating the propagation of macrophages and atherosclerosis [45]. The gene discussed is TPT1; the disease is atherosclerosis.