As a part of the effectively realized BPC 157/vascular-system interplay (lack of the adverse effect), there was the heart failure innate recovery as a whole (including counteracted various arrhythmias and counteracted thrombosis, blood pressures disturbances (intracranial (superior sagittal sinus), portal and caval hypertension, and aortal hypotension [19,24,27,29,31,37,38,39,40,84], or hypertension (hyperkalemia, NOS-blockade) [62,67] attenuated/eliminated peripherally and centrally). Here, NOS1 is linked to cardiac arrhythmia.