The expression of the proteins involved in glycolysis, GLUT1, HK2 and PFK1 decreased in ST CRC cells and increased in OR CRC cells relative to their respective ST CRC cells except that GLUT1 in SW480/OR and HK2 in SW620/OR were decreased compared to their respective PT and/or ST CRC cells (Figure 6A,B). Here, PFKM is linked to colorectal carcinoma.