Strong inhibitors of CYP3A enzymes include such antifungals as itraconazole, ketoconazole, and voriconazole; anticancer agents ceritinib, idelalisib, ribociclib, and tucatinib; macrolide antibiotics clarithromycin and telithromycin; antivirals (used to treat HIV infection) indinavir, nelfinavir, ritonavir, and saquinavir; an atypical antidepressant called nefazodone; and the drug mibefradil for hypertension and angina pectoris [202,203]. Here, CYP3A4 is linked to Hypertension.