The transcriptional activity of a number of proinflammatory cytokines/chemokines, such as IL-1, IL-6, IL-8, TNF-α, RANTES, MIF and ICAM1, is activated by NFκB signaling, demonstrating the key role of NFκB in the inflammatory response in endometriosis [49,50]. The gene discussed is CXCL8; the disease is endometriosis.