Individual IHC staining of NQO1, NRF1 and NRF2 enabled the observation of protein expression by DAB chromogen brown color intensity within normal cell types, such as bronchial epithelial cells, alveoli, mucosal glands, lymphoid cells, nerve cells, endothelial cells, fibroblasts, muscle cells and arteries (Figure 1), and cancer cells. This evidence concerns the gene NRF1 and cancer.