This Cur-elevated cisplatin-induced cytotoxicity in NSCLC has been linked to the downregulation of p38 MAPK-dependent X-ray repair cross-complementing group 1 (XRCC1) [78], an important mediator of DNA repair and the reparative process of cisplatin-mediated DNA injury in HepG2 cells [105]. Here, XRCC1 is linked to non-small cell lung carcinoma.