The classification for a third AD blood dataset was found to be acceptable (GSE140829AD, AUC 71% data not shown), while the classification within PD, FRDA, and FTD from controls was poor with probabilities for PD1 (AUC 67%), PD2 (AUC 67%), FRDA (AUC 63%), and FTD (AUC 70%) showing this set of transcript predictors has discriminating utility for classifying AD (Figure 3a). This evidence concerns the gene PAF1 and Alzheimer disease.