Coupling of these NPS with the tyrosine kinase inhibitor imatinib could target glucose transporter-1 (GLUT-1), both in rhabdomyosarcoma cells and in EWS PDX with different GLUT-1 expression levels with a 7.5% of efficiency [157], which make them a potential tool against GLUT-1-expressing tumors. Here, SLC2A1 is linked to rhabdomyosarcoma.