Furthermore, the CIMP+ subgroup showed significantly higher expression of ANTP homeobox oncogenes, as well as novel T-ALL genes including Phospholipase C Beta 4 protein coding gene (PLCB4), Plexin D1 protein coding gene (PLXND1), and Myosin XVIIIB protein coding gene (MYO18B). The gene discussed is PLCB4; the disease is acute lymphoblastic leukemia.