Seven gene targets were short-listed among the genes encoding for the proteins FOS that encodes for the leucine zipper protein, MMP7 (matrix metalloproteinase-7), and A2M (alpha-2-macroglobulin), were predicted to be more accurate diagnostic markers for pancreatic cancer, not only in serum, but also in urine samples [120]. This evidence concerns the gene A2M and familial pancreatic carcinoma.