First, using the ESTIMATEscore, we found high expression levels of SLC2A1 are related to low ImmuneScore, low StromalScore, and low ESTIMATEScore in most cancers, such as ACC, BLCA, BRCA, ESCA, HNSC, LUAD, OSCC, PAAD, PRAD, SARC, SKCM, STAD, TGCT, UCEC, and UCS (Figure S5A–O). This evidence concerns the gene SLC2A1 and cancer.