Contrasting to MYC in Burkitt lymphoma, for which variant translocations onto Ig light chain loci are common, BCL2 t(2;18) and t(18;22) variant translocations to light chain genes are rare in FL but found in 9% of chronic lymphocytic leukemia cases [3,4]. This evidence concerns the gene BCL2 and B-cell chronic lymphocytic leukemia.