This research highlighted many important immuno-oncology markers such as CD163, CSF1R, CSF1, PD-L1, IL10, TNFRSF14, TNFAIP8, PD-1, and FOXP3 which are markers of tumor-associated macrophages (TAMs), T lymphocytes, and regulatory T lymphocytes (Tregs). The gene discussed is CD274; the disease is neoplasm.