Heeke et al. studied the prevalence of HR-DDR deficiency across 21 tumor types including the following genes (ARID1A, ATM, ATRX, BAP1, BARD1, BLM, BRCA1/2, BRIP1, CHEK1/2, FANCA/C/D2/E/F/G/L, MRE11A, NBN, PALB2, RAD50, RAD51, RAD51B, and WRN). This evidence concerns the gene BRCA1 and neoplasm.