The results showed that LSECtin expression in colon cancer tissues was significantly positively correlated with stromal score (r = 0.547, p = 3.66 × 10−37), ESTIMAT immune score (r = 0.608, p = 1.1 × 10−42) (Figure 6A,B), TMB (p = 0.042) (Figure 6C), MSI (p = 0.029) (Figure 6D), and negatively correlated with mismatch repair gene MSH2 and EpCAM mutations (p < 0.05) (Figure 6E). The gene discussed is EPCAM; the disease is colonic neoplasm.