Interestingly, ZBTB4 is known to act as a tumor suppressor in various types of cancers (prostate cancer [76]; glioma [77]; colorectal cancer [78]; breast cancer [79]; Ewing sarcoma [80]), but more importantly, it is being investigated as a promissory anti-cancer druggable target. The gene discussed is ZBTB4; the disease is colorectal cancer.