ZBTB4 and adrenal cortex carcinoma: In the TCGA-ACC cohort, the three regulons with higher negative Spearman correlation with CENPA’s activity were THRB (Thyroid Hormone Receptor Beta), STAT5B (Signal Transducer and Activator of Transcription 5B), and ZBTB4 (Zinc Finger And BTB Domain Containing 4) (ρ = −0.87, −0.86, and −0.85, respectively, all p-values < 2.2 × 10−16).