Because the resistant HNSCC cell line CAL27/FP-R overexpress miR124-3p and miR766-3p, these cells showed reduced levels of CREBRF and NR3C2 and increased levels of CREB3/ATG5 and β-catenin/c-Myc as compared to control CAL27 cells (Figure 8B and Figure S7). The gene discussed is MYC; the disease is head and neck squamous cell carcinoma.