CTH and astrocytoma (excluding glioblastoma): In another study by Jurkowska et al. on the expression levels of CSE and 3MST in the astrocytoma U373 and neuroblastoma SH-SY5Y cell lines, higher expression of 3MST than CSE was reported, suggesting that 3MST is the major catalyzing enzyme of the sulfane sulfur pathway in neoplastic cells [133].