CDKN1B and colon adenocarcinoma: ZNF692 promotes cell proliferation, migration, and invasion in colon adenocarcinoma (COAD) by downregulating p27kip1 or upregulating cyclin D1, cyclin-dependent kinase 2 (CDK2), matrix metalloproteinase-9 (MMP-9), and PI3K/Akt signaling [25].