A few years later, Deng et al. [103] concluded that, in colorectal (LoVo and SW480 cell lines) cancer cells, the transcription factor MZF1 potentiates their tumorigenic capacity by transcriptionally activating the p55PIK protein, a regulatory subunit of IA-PI3K, which, in turn, activates the PI3K/Akt pathway. Here, MZF1 is linked to cancer.