MTOR and cancer: Interestingly, we found that these genes can inhibit the TSC/mTOR, RAS/MAPK, and PI3K/AKT pathways using the GSCA database, which are frequently activated in human cancers and control the uptake and utilization of a variety of nutrients, including glucose, amino acids, nucleotides, and lipids [45], while the aerobic glycolysis process—also known as the Warburg effect—is generally considered to be activated as a downstream effect, as regulated by the PI3K signaling pathway [46].