The epidermal growth factor receptor (EGFR) is a ubiquitously expressed receptor tyrosine kinase (RTK) and serves as a therapeutic target to treat cancers, such as non-small cell lung cancer (NSCLC), metastatic colorectal cancer (mCRC), and advanced head and neck cancer (HNC), which exhibit upregulated EGFR activity [7,8]. Here, EGFR is linked to metastatic colorectal cancer.